Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa

PHASE3TerminatedINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

March 31, 2011

Primary Completion Date

June 30, 2013

Study Completion Date

October 31, 2013

Conditions
Asymptomatic Parasitemia In Pregnancy
Interventions
DRUG

Azithromycin plus chloroquine

Study drug is a fixed dose tablet of AZCQ containing 250 mg AZ and 155 mg CQ base. All subjects will be administered a 3 day course of AZCQ IPTp regimen: a single dose of 1000 mg AZ/620 mg CQ base (4 fixed dose combination tablets of AZCQ: 250mg/155mg) administered per os (PO, orally) once daily for 3 days (Days 0, 1, 2).

Trial Locations (7)

1903

National Institute for Medical Research (Mwanza Centre)/ Nyamagana District Hospital, Mwanza

Unknown

Centre de Sante d'AHOUANSORI -AGUE, Cotonou

Hôpital Bethesda, Cotonou

Siaya District Hospital, Siaya

Zomba Central Hospital, Zomba

Teule Hospital, Muheza

Mulanda Health Centre IV, Kampala

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY