187
Participants
Start Date
September 30, 1999
Primary Completion Date
December 31, 2004
Study Completion Date
December 31, 2004
scaling and root planing
scaling and root planing as a single therapy
local tetracycline
local delivery of tetracycline fibers releasing approximately 1.7 mg/tooth in all pockets \>5mm
systemic metronidazole and amoxicillin
systemic metronidazole (250 mg tid x 14) and amoxicillin (500 mg bid x 14
surgery
periodontal surgery in residual pockets of \>4mm
local antibiotics and systemic metronidazole and amoxicillin
1.7 mg/tooth tetracycline fiber plus metronidazole (250 mg tid x14d)and amoxicillin (500 mg bid x 14d)
local tetracycline and periodontal surgery
local delivery of tetracycline fibers releasing approximately 1.7 mg/tooth in all pockets \>5mm and periodontal surgery in residual pockets of \>4mm
periodontal surgery and systemic metronidazole and amoxicillin
surgery in residual pockets \>4mm and metronidazole (250mg tidx14d) and amoxicillin (500mg bidx14d)
surgery, local tetracycline, systemic metronidazole and amoxicillin
periodontal surgery in residual pockets \>4mm, tetracycline ibers releasing approximately 1.7 mg/tooth in pockets \>5mm, systemic metronidazlo (250mg tidx14d) and amoxicillin (500 mg bidx14d)
The Forsyth Institute, Boston
Göteborg University
OTHER
Boston University
OTHER
The Forsyth Institute
OTHER