Combined Digital Colposcopy Analysis to Improve Cervical Precancer and Cancer Detection

PHASE2CompletedINTERVENTIONAL
Enrollment

551

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

September 1, 2016

Study Completion Date

November 9, 2016

Conditions
Cervical CancerPrecancerous Condition
Interventions
DEVICE

Multispectral Digital Colposcope (MDC)

"The MDC has 2 components: an optical probe \& a multispectral colposcope. The optical wand makes use of fluorescence \& reflectance spectroscopy; a light is shone on the cervix and the wand reports what it sees to a computer. Since cancer \& healthy cells interact differently with light, a computer can detect abnormalities. The multispectral colposcope is based on a conventional colposcope, which is already widely used. However, it is also able to produce fluorescence \& polarized reflectance images of the entire cervix. Computer analysis of these images can detect abnormalities on the cervix, defining their location and shape.~This trial involves combined analysis of MDC data. This may lead to more effective diagnosis of cervical abnormalities. The MDC will be used with standard care for patients presenting with cervical abnormalities (as detected by a Pap test). The MDC will not be used to guide patient management decisions.~All study subjects will receive this same intervention."

Trial Locations (3)

11212

Brookdale Hospital and Medical Center, Brooklyn

79905

Texas Tech Health Sciences Center, El Paso

V5Z 1M9

Vancouver General Hospital - Women's Clinic (G&L Diamond Centre), Vancouver

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

Texas Tech University Health Sciences Center

OTHER

collaborator

Brookdale University Hospital Medical Center

OTHER

collaborator

William Marsh Rice University

OTHER

collaborator

The University of Texas Health Science Center, Houston

OTHER

collaborator

M.D. Anderson Cancer Center

OTHER

lead

British Columbia Cancer Agency

OTHER

NCT01094132 - Combined Digital Colposcopy Analysis to Improve Cervical Precancer and Cancer Detection | Biotech Hunter | Biotech Hunter