Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 139 in Healthy Subjects and Subjects With Moderate to Severe Psoriasis

PHASE1CompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

April 11, 2010

Primary Completion Date

July 26, 2011

Study Completion Date

July 26, 2011

Conditions
Psoriasis
Interventions
DRUG

AMG 139

Six dose levels of AMG 139 administered as a single dose SC or IV in healthy volunteers (Part A) and subjects with moderate-severe psoriasis (Part B).

Trial Locations (4)

1010

Auckland Clinical Studies Ltd, Grafton

3004

Nucleus Network Limited, Melbourne

4006

QPharm Pty Limited, Herston

SA500

Clinical Medical and Analytical eXcellence (CMAX), Adelaide

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY