PF-00489791 For The Treatment Of Raynaud's

PHASE2CompletedINTERVENTIONAL
Enrollment

243

Participants

Timeline

Start Date

August 4, 2010

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions
Raynaud's DiseasePeripheral Vascular Disease
Interventions
DRUG

PF-00489791

Subjects with Secondary Raynaud's Phenomenon will receive PF-00489791 4 mg once a day for the first 4 week cross over period and then placebo once a day for the second 4 week cross over period

DRUG

PF-00489791

Subjects with Secondary Raynaud's Phenomenon will receive placebo once a day for the first 4 week cross over period and then PF-00489791 4 mg once a day for the second 4 week cross over period

DRUG

PF-00489791

Subjects with Secondary Raynaud's Phenomenon will receive PF-00489791 20 mg once a day for the first 4 week cross over period and then placebo once a day for the second 4 week cross over period

DRUG

PF-00489791

Subjects with Secondary Raynaud's Phenomenon will receive placebo once a day for the first 4 week cross over period and then PF-00489791 20 mg once a day for the second 4 week cross over period

DRUG

PF-00489791

Subjects with Primary Raynaud's Phenomenon will receive PF-00489791 4 mg once a day for the first 4 week cross over period and then placebo once a day for the second 4 week cross over period

DRUG

PF-00489791

Subjects with Primary Raynaud's Phenomenon will receive placebo once a day for the first 4 week cross over period and then PF-00489791 4 mg once a day for the second 4 week cross over period

DRUG

PF-00489791

Subjects with Primary Raynaud's Phenomenon will receive PF-00489791 20 mg once a day for the first 4 week cross over period and then placebo once a day for the second 4 week cross over period

DRUG

PF-00489791

Subjects with Primary Raynaud's Phenomenon will receive placebo once a day for the first 4 week cross over period and then PF-00489791 20 mg once a day for the second 4 week cross over period

Trial Locations (55)

1122

Semmelweis Egyetem, Ersebeszeti Klinika, Budapest

6000

Bacs-Kiskun Megyei Onkormanyzat Korhaza Szegedi Tudomanyegyetem AOK Oktato Korhaza, Kecskemét

9700

Vas Megyei Markusovszky Korhaz Nonprofit Zrt, Angiologiai Szakambulancia, Szombathely

12206

The Center for Rheumatology, Albany

13905

Regional Rheumatology Associates, Binghamton

14000

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City

14618

AAIR Research Center, Rochester

15706

Hospital Clinico Universitario Santiago de Compostela, Santiago de Compostela

16635

Altoona Center for Clinical Research, Duncansville

18015

East Penn Rheumatology Associates, PC, Bethlehem

19090

Rheumatic Disease Associates, Ltd., Willow Grove

20007

Georgetown University Hospital, Washington D.C.

20902

The Center for Rheumatology and Bone Research, Wheaton

21224

Johns Hopkins University - Division of Rheumatology, Baltimore

22391

Dermatologisches Ambulatorium Hamburg-Alstertal, Hamburg

28041

Hospital Universitario 12 de Octubre, Madrid

30342

Arthritis and Rheumatology of Georgia, Atlanta

44620

Unidad de Investigacion en Enfermedades Cronico Degenerativas, Guadalajara

46227

Diagnostic Rheumatology and Research, PC, Indianapolis

46601

Memorial Health System, Inc. dba Memorial Medical Group Clinical Research Institute, South Bend

48106

University of Michigan, Ann Arbor

48109

University of Michigan Health System, Ann Arbor

49546

West Michigan Rheumatology, PLLC, Grand Rapids

61107

Rockford Orthopedic Associates, Rockford

68516

Physician Research Collaboration, LLC, Lincoln

75231

Metroplex Clinical Research Center, Dallas

78200

Hospital Angeles. Centro Medico del Potosi, San Luis Potosí City

94063

Stanford Hospital and Outpatient Center, Redwood City

98057

Rainier Clinical Research Center, Inc., Renton

06030-5353

University of Connecticut Health Center, Farmington

01610

Clinical Pharmacology Study Group, Worcester

08903-0019

UMDNJ - Robert Wood Johnson Medical Center Clinical Research Center, New Brunswick

R3A 1M4

Arthritis Centre Health Sciences Centre, Winnipeg

N6A 4V2

St. Joseph's Health Centre, London

K1H 1A2

Rheumatology Research Associates, Ottawa

H3T 1E2

Sir Mortimer B. Davis, Jewish General Hospital, Montreal

0000

Centro Integral de Reumatologia e Inmunologia CIREI, Bogota

Fundacion Instituto de Reumatologia Fernando Chalem, Bogota

Idearg Sas, Bogotá

Servimed E.U, Bucaramanga

Medicity S.A.S, Bucaramanga

638 00

REVMATOLOGIE s.r.o.,, Brno

500 05

Fakultni nemocnice Hradec Kralove, Hradec Králové

128 50

Revmatologicky ustav, Prague

40-084

Slaskie Centrum Osteoporozy, Katowice

61-397

Prywatna Praktyka Lekarska Dr Med. Pawel Hrycaj, Poznan

Prywatna Praktyka Lekarska Prof. UM Dr hab. med. Pawel Hrycaj, Poznan

50-368

Katedra i Klinika Dermatologii, Wenerologii i Alergologii Akademii Medycznej we Wroclawiu, Wroclaw

110-744

Seoul National University Hospital, Rheumatology, Internal Medicine, Seoul

120-752

Yonsei University College of Medicine, Severance Hospital, Rheumatology, Internal Medicine, Seoul

137-701

The Catholic University of Korea, Seoul St. Mary's Hospital/ Rheumatology, Internal Medicine, Seoul

08003

Hospital Del Mar, Barcelona

413 45

CTC, Centrum för klinisk provning, Sahlgrenska Universitetssjukhuset, Gothenburg

221 85

Reumatologkliniken Skanes Universitetssjukhus Lund, Lund

171 76

Karolinska Universitetssjukhuset Solna, Reumatologiska kliniken, Stockholm

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY