Trial of the Use of Antenatal Corticosteroids in Developing Countries

NACompletedINTERVENTIONAL
Enrollment

103,117

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

March 31, 2014

Study Completion Date

April 30, 2014

Conditions
Preterm Birth
Interventions
BEHAVIORAL

Increasing use of Antenatal Corticosteroids (ACS)

"Intervention clusters:~* Increasing administration of ACS to pregnant women at high risk of preterm birth (HRPB) by providing health providers with kits containing dexamethasone, syringes, and instructions. Eligible women receive four injections of 6 mg dexamethasone from the kit or regimen of choice at the site.~* Improving identification of women at HRPB by diffusing recommendations for ACS use to health care providers, training health care providers to identify signs of preterm labor and eligibility criteria for ACS use, providing reminders to healthcare providers on the use of the kits, and using a color-coded tape to measure uterine height to estimate gestational age in women at HRPB with unknown gestational age.~Control clusters: no specific intervention for comparison. Both intervention and control clusters: Birth attendants trained in essential newborn care of LBW infants and instructed to teach mothers how to provide care to premature infants."

Trial Locations (7)

Unknown

Institute for Clinical Effectiveness and Health Policy (IECS), Buenos Aires

Universidad Francisco Marroquin Facultad de Medicina, Guatemala City

JN Medical College, Belagavi

Lata Medical Research Foundation, Nagpur

Moi University School of Medicine, Eldoret

Aga Khan University, Karachi

University of Zambia, Lusaka

All Listed Sponsors
collaborator

RTI International

OTHER

collaborator

Tulane University School of Medicine

OTHER

collaborator

Institute for Clinical Effectiveness and Health Policy

OTHER

collaborator

University of Alabama at Birmingham

OTHER

collaborator

University Teaching Hospital, Lusaka, Zambia

OTHER

collaborator

University of Colorado, Denver

OTHER

collaborator

Universidad Francisco Marroquín

OTHER

collaborator

Jawaharlal Nehru Medical College

OTHER

collaborator

Christiana Care Health Services

OTHER

collaborator

Aga Khan University

OTHER

collaborator

Columbia University

OTHER

collaborator

Indiana University

OTHER

collaborator

Moi Univeristy

OTHER

collaborator

Lata Medical Research Foundation, Nagpur

OTHER

collaborator

Massachusetts General Hospital

OTHER

lead

NICHD Global Network for Women's and Children's Health

NETWORK

NCT01084096 - Trial of the Use of Antenatal Corticosteroids in Developing Countries | Biotech Hunter | Biotech Hunter