A Dose-Finding Study of Topiramate (JNS019) in Participants With Migraine

PHASE2CompletedINTERVENTIONAL
Enrollment

387

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

January 31, 2009

Study Completion Date

January 31, 2009

Conditions
Migraine
Interventions
DRUG

Topiramate

In the titration period, topiramate 25-mg tablet once daily orally for 1 week, the dose will be increased by 1 tablet every week up to twice daily for a total of 4 weeks so that the total daily dose given is 50 mg or 100mg. The dose given in the final titration week will be continued for further 18 weeks (fixed dose period).

DRUG

Placebo

In the titration period, matching placebo tablet once daily orally for 1 week, the dose will be increased by 1 tablet every week up to twice daily for a total of 4 weeks. The dose given in the final titration week will be continued for further 18 weeks (fixed dose period).

Trial Locations (29)

Unknown

Bunkyō City

Chitose

Hachiōji

Iruma

Isehara

Kagoshima

Kamogawa

Kitakyushu

Kobe

Kumamoto

Kyoto

Minato

Morioka

Nagoya

Nishinomiya

Numakunai

Sagamihara

Sapporo

Shimotsuga

Shinjuku

Shinjuku-Ku

Shizuoka

Suginami-Ku

Tokyo

Toyama

Toyonaka

Ube

Yokohama

Yonago

Sponsors
All Listed Sponsors
lead

Janssen Pharmaceutical K.K.

INDUSTRY

NCT01081795 - A Dose-Finding Study of Topiramate (JNS019) in Participants With Migraine | Biotech Hunter | Biotech Hunter