Cytomegalovirus - Immunoprophylactic Adoptive Cellular Therapy Study

PHASE3CompletedINTERVENTIONAL
Enrollment

89

Participants

Timeline

Start Date

July 31, 2008

Primary Completion Date

September 30, 2014

Study Completion Date

October 31, 2014

Conditions
Cytomegalovirus Infection
Interventions
BIOLOGICAL

Adoptive Cellular Therapy

CMV-specific T-cells, single infusion at 27 days post-HSCT

DRUG

Best available antiviral drug therapy

"1. Intravenous ganciclovir 5mg/kg twice daily~2. Oral valganciclovir 900mg twice daily~3. Intravenous foscarnet 90 mg/kg twice daily"

Trial Locations (14)

Unknown

Birmingham Heartlands Hospital, Birmingham

Queen Elizabeth Hospital, Birmingham

Beatson West of Scotland Cancer Centre, Glasgow

Royal Liverpool Hospital, Liverpool

Kings College Hospital, London

Royal Free Hospital, London

Christie Hospital, Manchester

Manchester Royal Infirmary, Manchester

City Hospital, Nottingham

Southampton General Hospital, Southampton

LS9 7TF

St James's University Hospital, Leeds

BS2 8BJ

Bristol Royal Hospital for Children, Bristol

CB2 0QQ

Addenbrookes Hospital, Cambridge

WC1E 6BT

University College Hospital, London

Sponsors

Lead Sponsor

Collaborators (2)

All Listed Sponsors
collaborator

Wellcome Trust

OTHER

collaborator

EMAS Pharma

INDUSTRY

collaborator

Commitum AB

INDUSTRY

collaborator

BioAnaLab

UNKNOWN

lead

Cell Medica Ltd

INDUSTRY