NCT01073670View on ClinicalTrials.gov

Indomethacin and Cardiac Bypass Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

August 31, 2000

Primary Completion Date

April 30, 2002

Study Completion Date

April 30, 2002

Conditions
Hemorrhage
Interventions
DRUG

Indomethacin

Indomethacin was given via suppository at time of induction for anesthesia (2 x 50 mg) followed by one 50 mg suppository at 6, 12, 18 and 24 hours following cardiac bypass surgery.

DRUG

Acetaminophen & Indomethacin

Subjects were given a loading dose of acetaminophen (1300 mg) and indomethacin (50 mg)by suppository at the time of induction for anesthesia and then given 650mg acetaminophen + 25 mg indomethacin at 6, 12, 18 and 24 hours following cardiac bypass surgery.

DRUG

Acetaminophen

Subjects were given a loading dose of 2600 mg of acetaminophen (via suppository) at time of induction for anesthesia then given 1300mg at 6, 12, 18 and 24 hours following cardiac bypass surgery.

Trial Locations (1)

K7L 2V7

Kingston General Hospital, Kingston

All Listed Sponsors
lead

Queen's University

OTHER

NCT01073670 - Indomethacin and Cardiac Bypass Surgery | Biotech Hunter | Biotech Hunter