Study of Effects of Tenofovir on Bone Health and Kidneys During Pregnancy and Breastfeeding

CompletedOBSERVATIONAL
Enrollment

1,765

Participants

Timeline

Start Date

March 22, 2011

Primary Completion Date

November 30, 2015

Study Completion Date

November 30, 2015

Conditions
HIV Infections
Interventions
DRUG

Tenofovir disoproxil fumarate (TDF)

Some participants will receive varying doses of TDF during pregnancy or breastfeeding as part of the larger study (IMPAACT 1077 PROMISE).

Trial Locations (11)

1862

Soweto IMPAACT CRS, Johannesburg

2001

Shandukani Research CRS, Johannesburg

4001

Durban Paediatric HIV CRS, Durban

Umlazi CRS, Durban

7505

Family Clinical Research Unit (FAM-CRU) CRS, Tygerberg

Unknown

Blantyre CRS, Blantyre

Malawi CRS, Lilongwe

MU-JHU Research Collaboration (MUJHU CARE LTD) CRS, Kampala

Seke North CRS, Chitungwiza

St Mary's CRS, Chitungwiza

Harare Family Care CRS, Harare

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

Gilead Sciences

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH