Study to Evaluate the Effects of Oral Administration of Lixivaptan in Patients With Congestive Heart Failure

PHASE2CompletedINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

January 31, 2010

Primary Completion Date

September 30, 2010

Conditions
Congestive Heart Failure
Interventions
DRUG

Lixivaptan

Capsule. Patients will be screened for entry into the study and will be randomized (2:1) to lixivaptan or placebo. One hundred (100) patients will be randomized to receive lixivaptan 100 mg once daily (QD) for 8 weeks. Fifty (50) placebo patients will receive matching oral placebo for 8 weeks.

DRUG

Placebo

Patients will be screened for entry into the study and will be randomized (2:1) to lixivaptan or placebo.

Trial Locations (25)

14787

Great Lakes Medical Research, Westfield

23294

National Clinical Research - Richmond, Richmond

23502

National Clinical Research - Norfolk, Inc., Norfolk

27610

Raleigh Cardiology, Raleigh

30096

In-Quest Medical Research, LLC, Duluth

30342

Executive Health and Research Associates, Inc, Atlanta

32141

Edgewater Medical Research Inc, Edgewater

33040

Foundation/Research/Cardiovascular Specialists Lower Keys, Key West

33624

Tampa Clinical Research, Tampa

33756

Innovative Research of West Florida, Inc, Clearwater

33952

Charlotte Heart Group Research Center, Port Charlotte

36608

Mobile Heart Specialists, PC, Mobile

44718

Clinical Research Limited, Canton

45414

Dayton Heart Center, Dayton

60504

Fox Valley Clinical Research Center, Aurora

63141

Horizon Research, St Louis

72401

Nea Clinic, Jonesboro

75231

Cardiovascular Research Institute of Dallas, Dallas

77002

East Texas Cardiology, Houston

85029

Phoenix Clinical, Phoenix

92868

Orange County Heart Institute and Research Center, Orange

95340

Merced Heart Associates, Merced

95608

Capitol Interventional Cardiology, Carmichael

04210

Maine Research Associates, Auburn

01432

Primary Care Cardiology Research, Inc, Ayer

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Cardiokine Biopharma, LLC

INDUSTRY

lead

CardioKine Inc.

INDUSTRY

NCT01055912 - Study to Evaluate the Effects of Oral Administration of Lixivaptan in Patients With Congestive Heart Failure | Biotech Hunter | Biotech Hunter