Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders

PHASE2CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

January 31, 2010

Primary Completion Date

November 30, 2011

Study Completion Date

December 31, 2011

Conditions
Hepatitis C
Interventions
DRUG

CTS-1027

CTS-1027 supplied in 5 and 10 mg tablets, 15 mg taken twice daily, for up to 48 weeks

DRUG

Pegylated interferon

Pegylated interferon, 180 micrograms in 0.5 ml of solution injected subcutaneously (SQ) once per week, for up to 48 weeks. Packaged in single use syringes.

DRUG

Ribavirin

Ribavirin, 200 mg capsules taken in two divided daily doses totaling 1000 mg (5 capsules) for patients weighing 75 kg or less, or 1200 mg (6 capsules) for patients weighing more than 75 kg for up to 48 weeks.

Trial Locations (15)

23602

Liver Institute of Virginia, Newport News

30309

Digestive Healthcare of Georgia, Atlanta

45219

Consultants of Clinical Research, Ohio GI and Liver Institute, Cincinnati

48377

Henry Ford Medical Center-Columbus, Novi

55446

MN Clinical Research Center, Plymouth

63104

St. Louis University, St Louis

70112

Tulane University Health Sciences Center, New Orleans

77030

Advanced Liver Therapies - Baylor College of Medicine, Houston

VA Medical Center, Houston, Houston

80113

South Denver Gastroenterology, Englewood

80262

University of Colorado Health Science Center, Denver

84132

University of Utah Health Science Center, Salt Lake City

92037

Scripps Clinic, La Jolla

92161

VA Medical Center, San Diego, San Diego

00909

Fundacion de Investigacion de Diego, Santurce

Sponsors
All Listed Sponsors
lead

Conatus Pharmaceuticals Inc.

INDUSTRY

NCT01051921 - Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders | Biotech Hunter | Biotech Hunter