Autologous Hematopoietic Cell Transplantation for Core-binding Factor Acute Myeloid Leukemia

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 11, 2010

Primary Completion Date

October 30, 2018

Study Completion Date

October 30, 2018

Conditions
Leukemia, Myeloid
Interventions
PROCEDURE

autologous hematopoietic cell transplantation

"1. Autologous peripheral blood stem cell (PBSCs) harvesting~ * After the second cycle of high-dose ara-C(HDAC) consolidation chemotherapy~ * Mobilization: recombinant human G-CSF(Filgrastim) 5mcg/kg s.c. daily starting on 10 days after start of the second cycle of HDAC chemotherapy~ * Harvest procedure: peripheral blood mononuclear cells will be collected. Target CD34+ cell dose is over 5x10E6/kg.~2. Conditioning regimen for autologous HCT~ * Busulfan 3.2 mg/kg/day i.v. daily on days -7 to -5 (for 3 days)~ * Etoposide 400mg/m2/day i.v. daily on days -3 to -2 (for 2 days)~3. Autologous cell infusion and waiting for engraftment"

Trial Locations (11)

431796

Hallym University Sacred Heart Hospital, Anyang

570749

Wonkwang University Hospital, Iksan

602702

Kosin University, Gospel Hospital, Busan

614735

Busan Paik Hospital, Inje University College of Medicine, Busan

660702

Gyeongsang National University Hospital, Jinju

682714

Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan

701600

Daegu Fatima Hospital, Daegu

705717

Yeongnam University Hospital, Daegu

705718

Daegu Catholic University Medical Center, Daegu

405-760

Gachon University Gil Hospital, Inchon

138-736

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
lead

Asan Medical Center

OTHER