Study of XL147 (SAR245408) in Combination With Trastuzumab or Paclitaxel and Trastuzumab in Subjects With Metastatic Breast Cancer Who Have Progressed on a Previous Trastuzumab-based Regimen

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

February 28, 2010

Primary Completion Date

December 31, 2012

Study Completion Date

December 31, 2012

Conditions
Breast CancerBreast Neoplasms
Interventions
DRUG

XL147 (SAR245408)

administered orally once daily as tablet(s)

BIOLOGICAL

trastuzumab

administered by IV once every 3 weeks

DRUG

paclitaxel

administered by IV once every week

Trial Locations (9)

10032

Investigational Site Number 1150, New York

10467

Investigational Site Number 1151, The Bronx

28041

Investigational Site Number 3413, Madrid

33901

Investigational Site Number 1238, Fort Meyers

37203

Investigational Site Number 1214, Nashville

37232

Investigational Site Number 1246, Nashville

48201

Investigational Site Number 1330, Detroit

90033

Investigational Site Number 1537, Los Angeles

02115

Investigational Site Number 1138, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Sanofi

INDUSTRY