NCT01042496View on ClinicalTrials.gov

Bipolar Depression Before and After Lamotrigine Treatment

PHASE3CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

December 31, 2009

Primary Completion Date

September 30, 2014

Study Completion Date

October 31, 2014

Conditions
Bipolar Depression
Interventions
DRUG

Lamotrigine

12 week open trial: 25mg/day for 2 weeks, 50mg/day for 2 weeks, 100mg/day for 2 weeks, 200mg/day for 6 weeks. Flexible titration for early response and/or side effects.

PROCEDURE

1H-MR

Proton magnetic resonance spectroscopy (1H-MR) evaluation of medial anterior cingulate cortex (MACC) and left dorsal lateral prefrontal cortex (LDLPC).

Trial Locations (1)

55905

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

Mayo Clinic
All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Mayo Clinic

OTHER