Effect of Nebivolol on Oxidative Stress and Endothelial Progenitor Cells

PHASE4CompletedINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

December 31, 2009

Primary Completion Date

December 31, 2013

Study Completion Date

December 31, 2013

Conditions
Hypertension
Interventions
DRUG

Nebivolol

Nebivolol 5 mg PO qday for 2 weeks, titrated up to Nebivolol 10 mg PO qday if BP is \>125/80 for the 2 more weeks, and then titrated up to Nebivolol 20 mg PO qday if BP is \>125/80 for the remaining 8 weeks

DRUG

Metoprolol succinate

Metoprolol 50 mg PO qday for 2 weeks, titrated up to Metoprolol 100 mg PO qday if BP is \>125/80 for the 2 more weeks, and then titrated up to Metoprolol 200 mg PO qday if BP is \>125/80 for the remaining 8 weeks

Trial Locations (1)

30322

Emory University, Atlanta

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Forest Laboratories

INDUSTRY

lead

Emory University

OTHER