Expanded Natural Killer (NK) Cells for Multiple Myeloma Study

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

September 30, 2016

Study Completion Date

November 30, 2020

Conditions
Multiple Myeloma
Interventions
OTHER

Treatment with in vitro expanded haploidentical NK cells

10 expanded NK-DLI will be applied at fixed intervals and to each patient within 30 days (3 applications per week, Mo/We/Fr) starting with increasing CD56+CD3- NK cell doses at 3 dose levels (1.5x10e6/kg, 1.5x10e7/kg and 1x10e8/kg) and, if safe, continuing with maximally 7 doses of 1x10e8/kg. Maximal cumulative T-cell dose is fixed at \<1x10e5/kg

Trial Locations (1)

4031

University Hospital, Basel

All Listed Sponsors
lead

University Hospital, Basel, Switzerland

OTHER

NCT01040026 - Expanded Natural Killer (NK) Cells for Multiple Myeloma Study | Biotech Hunter | Biotech Hunter