A Two Part Trial Investigating the Safety of NN9924 in Healthy Male Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

155

Participants

Timeline

Start Date

December 17, 2009

Primary Completion Date

May 7, 2010

Study Completion Date

May 7, 2010

Conditions
DiabetesDiabetes Mellitus, Type 2Healthy
Interventions
DRUG

NN9924 (oral)

Subjects will be randomized to receive a single dose of NN9924, at escalating dose levels. Progression to next dose will be based on safety evaluation.

DRUG

placebo

Subjects will receive a single dose of placebo as a comparator to NN9924, at all dose levels.

DRUG

NN9924 (oral)

Subjects will be randomized to receive a single dose of NN9924 in one of three different concentrations. The dose will be selected based on the results of part 1.

DRUG

placebo

Subjects will be randomized to receive a single dose of placebo.

DRUG

NN9924 (s.c.)

As an active comparator, one standard dose will be given s.c. (under the skin) at one study visit

DRUG

NN9924 (i.v.)

As an active comparator, one standard dose will be given i.v. (into the vein) at one study visit.

Trial Locations (1)

HA1 3UJ

Novo Nordisk Investigational Site, Harrow

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY