Recombinant Human C1 Inhibitor for the Treatment of Early Antibody-Mediated Rejection in Renal Transplantation

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

December 31, 2010

Primary Completion Date

December 31, 2011

Study Completion Date

December 31, 2011

Conditions
Graft RejectionKidney Transplantation
Interventions
PROCEDURE

plasmapheresis and IVIG

Plasmapheresis with either 5% human albumin or FFP replacement, plus IVIG 100mg/kg IV after each PP session, every other day x 5 treatments

DRUG

recombinant C1 inhibitor

100units/kg IV for seven consecutive days (once daily on PP/IVIG days, twice daily on non-PP/IVIG days).

Trial Locations (1)

53792

University of Wisconsin, Madison

Sponsors
All Listed Sponsors
collaborator

University of Wisconsin, Madison

OTHER

lead

Pharming Technologies B.V.

INDUSTRY