A Two Part Trial Investigating NN1952 in Healthy Subjects and Subjects With Type 1 and Type 2 Diabetes

PHASE1CompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

November 30, 2009

Primary Completion Date

June 30, 2010

Study Completion Date

June 30, 2010

Conditions
DiabetesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Healthy
Interventions
DRUG

NN1952

Subjects will be randomised to receive a single dose of NN1952, at escalating dose levels. Progression to next dose will be based on safety evaluation.

DRUG

insulin aspart

As an active comparator, one standard dose will be given s.c. (under the skin) at all dose levels.

DRUG

placebo

Subjects will receive a single dose of placebo as a comparator to NN1952, at all dose levels.

DRUG

NN1952

Subjects will be randomised to receive a single dose of NN1952 with or without a meal, on two of four separate study visits. The dose will be selected based on the results of part 1.

DRUG

insulin aspart

As an active comparator, one standard dose will be given s.c. (under the skin) at one study visit.

DRUG

placebo

Subjects will receive a single dose of placebo as a comparator to NN1952 at one study visit.

Trial Locations (1)

41460

Novo Nordisk Investigational Site, Neuss

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY