PCI-24781 in Combination With Doxorubicin to Treat Sarcoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

March 31, 2015

Study Completion Date

March 31, 2015

Conditions
Sarcoma
Interventions
DRUG

PCI-24781

Capsules taken orally for 5 consecutive days starting on Day 1 of each 3 week cycle

DRUG

Doxorubicin

Administered intravenously on Day 4 of each 3 week cycle

DRUG

GCSF

Administered on Day 5 of each 3 weeks cycle in Arm 1 if determined to be clinically indicated, and in all patients enrolled into Arm 2

Trial Locations (2)

02114

Massachusetts General Hospital, Boston

02115

Dana-Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

Pharmacyclics LLC.

INDUSTRY