Radiosurgery and Avastin for Recurrent Malignant Gliomas

NACompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

December 31, 2009

Primary Completion Date

March 31, 2011

Study Completion Date

February 29, 2012

Conditions
Malignant Glioma
Interventions
RADIATION

Stereotactic Radiosurgery (SRS)

Tumor Volume \< 2.0cm receives 24 Gy in 1 fraction Tumor Volume 2.0-2.9cm receives 18 Gy in 1 faction Tumor Volume 3.0-4.9cm receives 25 Gy in 5Gy/fraction

DRUG

Bevacizumab

Bevacizumab (Avastin) 10 mg/kg given the day before SRS and 2 weeks after SRS

Trial Locations (1)

27710

Duke University Medical Center, Radiation Oncology, Durham

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

Duke University

OTHER

NCT01017250 - Radiosurgery and Avastin for Recurrent Malignant Gliomas | Biotech Hunter | Biotech Hunter