NCT01016769 - Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 30, 2009

Primary Completion Date

June 30, 2018

Study Completion Date

June 30, 2018

Conditions

Squamous Cell CancerHead and Neck Cancer

Interventions

DRUG

Temsirolimus + Weekly Paclitaxel + Carboplatin

"Temsirolimus Per dose escalation scheme Level 1 (15 mg) 2 (20 mg) Level 3 (25 mg) IVPB 30 minutes weekly (3 weeks on, 1 week off) days 1 and 8.~Paclitaxel 80 mg/m2 IVPB 1 hour weekly (2 weeks on, 1 week off) days 1 and 8. Carboplatin AUC 1.5 IVPB 30 minutes days 1 and 8. On Day 15 of each cycle, patients begin the rest week."

Trial Locations (5)

10065

Memorial Sloan Kettering Cancer Center, New York

10591

Memorial Sloan Kettering Cancer Center at Phelps Memorial Hospital Center, Sleepy Hollow

11725

Memorial Sloan Kettering Cancer Center @ Suffolk, Commack

07939

Memorial Sloan Kettering Cancer Center at Basking Ridge, Basking Ridge

Unknown

Memorial Sloan Kettering at Mercy Medical Center, Rockville Centre