Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients

PHASE2/PHASE3UnknownINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 30, 2009

Primary Completion Date

November 30, 2011

Study Completion Date

December 31, 2011

Conditions
Beta-ThalassemiaBone Marrow Transplantation
Interventions
DRUG

Zoledronic acid

Zoledronic acid 4 mg adjusted dose based on renal function IV 15-minute infusion every 3 months for a total of one year ( 4 doses ) beginning as soon as possible after randomization.

DRUG

Placebo

Placebo

Trial Locations (1)

14114

Hematology-Oncology & SCT Research Center, Tehran

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

Tehran University of Medical Sciences

OTHER