Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias

PHASE3RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 26, 2021

Primary Completion Date

August 31, 2024

Study Completion Date

August 31, 2024

Conditions
Sudden Cardiac DeathVentricular TachycardiaVentricular FibrillationCardiomyopathy
Interventions
PROCEDURE

Cardiac Sympathetic Denervation (CSD)

Cardiac sympathetic denervation is performed using an endoscopic procedure called VATS (video-assisted thoracoscopic sympathectomy). The surgeon removes the lower half of the stellate ganglia in addition to the thoracic ganglia of T2 - T4 on both the right and left side. The VATS procedure provides a minimally invasive endoscopic approach that is safe and effective. The procedure can be completed in less than 45 minutes on each side.

DRUG

Routine Care

Anti-arrhythmic medications are continued for the duration of the study unless discontinued or adjusted to due to drug toxicity, intolerance, or ICD shock. All anti-arrhythmic medications (whether in the routine care or surgical arm) can be adjusted at the discretion of the treating physician.

Trial Locations (3)

37235

RECRUITING

Vanderbilt University, Nashville

90095

RECRUITING

UCLA Health, Los Angeles

97239

RECRUITING

OHSU, Portland

All Listed Sponsors
collaborator

Oregon Health and Science University

OTHER

lead

University of California, Los Angeles

OTHER

NCT01013714 - Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias | Biotech Hunter | Biotech Hunter