Effect of Angiotensin Receptor Blockade on Insulin Resistance and Adipose Tissue Cytokines in Type 2 Diabetes

NACompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

January 31, 2004

Primary Completion Date

October 31, 2007

Study Completion Date

August 31, 2009

Conditions
Insulin ResistanceType 2 Diabetes
Interventions
PROCEDURE

Hyperinsulinaemia

Hyperinsulinaemic (1 mIU/kg/min) euglycaemic (5 mmol/l) clamp

DRUG

Losartan

Acute administration of losartan 200mg total prior to clamp

DRUG

Saline

Infusion of Saline as a volume control intervention

Trial Locations (1)

14021

Diabetes Center, Institute of Clinical and Experimental Medicine, Prague

All Listed Sponsors
collaborator

Ministry of Health, Czech Republic

OTHER_GOV

lead

Institute for Clinical and Experimental Medicine

OTHER_GOV

NCT01011062 - Effect of Angiotensin Receptor Blockade on Insulin Resistance and Adipose Tissue Cytokines in Type 2 Diabetes | Biotech Hunter | Biotech Hunter