NCT01009359 - Evaluation of the Neuroinflammation Pattern of BAY85-8102 F-18, DPA-714 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of F 18, DPA-714 in Healthy Volunteers | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

July 31, 2010

Study Completion Date

October 31, 2010

Conditions

Diagnostic Imaging

Interventions

DRUG

F-18 DPA-714 (BAY85-8102)

Alzheimer Disease patients: Single intervenous bolus injection of 250 MBq BAY85-8102 on day one of the treatment period, PET/CT

DRUG

F-18 DPA-714 (BAY85-8102)

Healthy volunteers for brain imaging: Single intervenous bolus injection of 250 MBq BAY85-8102 on day one of the treatment period, PET/CT

DRUG

F-18 DPA-714 (BAY85-8102)

Healthy volunteers for whole body imaging: Single intervenous bolus injection of 150 MBq BAY85-8102, whole body PET/CT for evaluation of effective dose, kinetics of BAY85-8102 in blood

Trial Locations (2)

20520

Turku

1081 HV

Amsterdam