Temsirolimus (Torisel®) and Erlotinib (Tarceva®) in Platinum-Refractory/Ineligible, Advanced, Squamous Cell Carcinoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

December 31, 2009

Primary Completion Date

September 30, 2012

Study Completion Date

December 31, 2012

Conditions
Squamous Cell Carcinoma
Interventions
DRUG

Erlotinib

Treatment will continue until disease progression, unacceptable toxicity, or withdrawal of informed consent.

DRUG

Temsirolimus

In the absence of Grade 3 or higher toxicity, a single, intra-patient dose increase of temsirolims to 20 mg intravenously weekly is permitted after the first 28 day cycle. Treatment will continue until disease progression, unacceptable toxicity, or withdrawal of informed consent.

Trial Locations (2)

87102

University of New Mexico Cancer Center @ Lovelace Medical Center, Albuquerque

87106

University of New Mexico Cancer Center, Albuquerque

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

New Mexico Cancer Research Alliance

OTHER