33
Participants
Start Date
November 30, 2009
Primary Completion Date
January 31, 2020
Study Completion Date
August 31, 2020
New Medication: Enalapril, Isradipine, Propranolol
"Enalapril will be added in the evening at 8 pm. If the subject is already on an ACEI or there is a contraindication to starting an ACEI the subject will be started on isradipine instead. If the subject is already on an ACEI and calcium channel blocker at baseline, propranolol will then be the new medication added.~Dosing will be as follows:~ACEI: Enalapril \< 40 kg starting dose 2.5 mg titrate to 5 mg \> 40 kg starting dose 5 mg titrate to 10mg Calcium Channel Blocker: Isradipine \< 40 kg 2.5 mg \> 40 kg starting dose 2.5 mg titrate to 5 mg Beta Blocker: Propranolol \<40 kg starting dose 10 mg titrate to 20 mg \>40 kg starting dose 20 mg titrate to 40 mg"
Cohen Children's Medical Center of NY, New Hyde Park
Children's Hospital of Philadelphia, Philadelphia
Lead Sponsor
Children's Hospital of Philadelphia
OTHER
Northwell Health
OTHER