THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA)

PHASE3TerminatedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

January 31, 2010

Primary Completion Date

June 30, 2010

Study Completion Date

June 30, 2010

Conditions
Sickle Cell Disease
Interventions
OTHER

High Demand / Low Infusion

HDLI dosing plan will administer either morphine or hydromorphone using PCA. Dosing will be based on body weight.

OTHER

PCA Dosing Plan

LDHI dosing plan will administer either morphine ot hydromorphone using PCA. Dosing will be based on body weight.

Trial Locations (28)

Unknown

Children's Hospital and Research Center, Oakland

Yale-New Haven Medical Center,, New Haven

A.I. duPont Hospital for Children, Wilmington

Children's National Medical Center, Washington D.C.

Howard University Hospital, Washington D.C.

Emory University School of Medicine, Atlanta

Medical College of Georgia, Augusta

Children's Memorial Hospital, Chicago

University of Illinois Sickle Cell Center, Chicago

Kosair Children's Hospital, Louisville

Children's Hospital at Sinai, Baltimore

Johns Hopkins, Baltimore

National Institutes of Health Clinical Center, Bethesda

Boston Medical Center, Boston

Children's Hospital Boston, Boston

University of Mississippi Medical Center, Jackson

Interfaith Medical Center, Brooklyn

New York Methodist Hospital, Brooklyn

The University of North Carolina at Chapel Hill, Chapel Hill

Duke University Medical Center, Durham

Cincinnati Children's Hospital Medical Center, Cincinnati

Nationwide Children's Hospital, Columbus

Ohio State University, Columbus

Children's Hospital of Philadelphia, Philadelphia

St. Christopher's Hospital for Children, Philadelphia

Children's Hospital of Pittsburgh, Pittsburgh

Texas Children's Hospital, Houston

Virginia Commonwealth University Health Systems, Richmond

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Carelon Research

OTHER