NCT00996034 - Nicotine Vaccination and Nicotinic Receptor Occupancy | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 30, 2009

Primary Completion Date

February 28, 2011

Study Completion Date

February 28, 2011

Conditions

Nicotine Dependence

Interventions

BIOLOGICAL

NicVAX

1.0 mL of Nicotine Conjugate Vaccine(x4), I.M. at 3 week intervals between SPECT studies

RADIATION

[123I]5-IA-85380

up to 10 mCi of \[123I\]5-IA-85380, I.V. on each of two SPECT Scan days

DRUG

Nicotine bitartrate

0.5-1.5 mg of Nicotine bitartrate, I.V. on each of two SPECT Scan days

Trial Locations (1)

Veterans Association Connecticut Hospital System, West Haven