Assessing the Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis on the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines

PHASE4CompletedINTERVENTIONAL
Enrollment

224

Participants

Timeline

Start Date

September 30, 2009

Primary Completion Date

June 30, 2010

Study Completion Date

February 28, 2011

Conditions
Rheumatoid Arthritis
Interventions
OTHER

Placebo

Placebo - Two 0.9% saline subcutaneous (sc) injections at Week 0, Week 2, and Week 4 followed by two sc injections of Open-Label (OL) CZP 200 mg at Weeks 6, 8 and 10, then one sc injection of OL CZP 200 mg every two weeks from Week 12 until last drug administration (up to Week 32).

BIOLOGICAL

Certolizumab pegol

Certolizumab pegol - Two 200 mg subcutaneous (sc) injections at Week 0, Week 2, and Week 4 followed by one sc injection of Open-Label (OL) CZP 200 mg from Week 6 until last drug administration (up to Week 32).

Trial Locations (41)

Unknown

Birmingham

Huntsville

Tuscaloosa

Peoria

Scottsdale

Tucson

Los Angeles

Palm Desert

Santa Maria

Santa Monica

Aventura

Fort Lauderdale

Melbourne

Orange Park

Palm Harbor

Venice

Vero Beach

Zephyrhills

Idaho Falls

Meridian

Cedar Rapids

Kalamazoo

Lansing

Hattiesburg

Florissant

Reno

Brooklyn

Smithtown

Syracuse

Asheville

Charlotte

Middleburg Heights

Oklahoma City

Duncansville

Erie

West Reading

Myrtle Beach

Orangeburg

San Antonio

Seattle

Oak Creek

Sponsors

Lead Sponsor

All Listed Sponsors
lead

UCB Pharma

INDUSTRY

NCT00993668 - Assessing the Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis on the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines | Biotech Hunter | Biotech Hunter