Red Cell Storage Duration Study

PHASE3CompletedINTERVENTIONAL
Enrollment

1,481

Participants

Timeline

Start Date

January 31, 2010

Primary Completion Date

March 31, 2014

Study Completion Date

March 31, 2014

Conditions
Cardiac SurgeryErythrocyte Transfusion
Interventions
BIOLOGICAL

Red blood cell units stored <= 10 days

Pre-storage leukoreduced red blood cell units stored \<=10 days at time of transfusion. Can be AS1, AS3, or AS5. Frozen, deglycerolized, washed, and volume-reduced products are protocol violations.

BIOLOGICAL

Red blood cell units stored >= 21 days

Pre-storage leukoreduced red blood cell units stored \>=21 days at time of transfusion. Can be AS1, AS3, or AS5. Frozen, deglycerolized, washed, and volume-reduced products are protocol violations.

Trial Locations (33)

10032

Columbia University Health Center, New York

10065

Weill Cornell Medical School, New York

15213

University of Pittsburgh Presbyterian and Shadyside, Pittsburgh

15219

UPMC-Mercy Hospital, Pittsburgh

21201

University of Maryland, Baltimore

21287

Johns Hopkins University, Baltimore

27599

University of North Carolina at Chapel Hill, Chapel Hill

27713

Duke University, Durham

30322

Emory University, Atlanta

32610

University of Florida, Gainesville

37323

Vanderbilt University Medical Center, Nashville

46802

St. Joseph Hospital, Fort Wayne

46804

Indiana/Ohio Heart, Fort Wayne

52242

University of Iowa, Iowa City

53201

Froedtert Memorial Lutheran Hospital, Milwaukee

53215

Aurora St. Lukes Medical Center, Milwaukee

54401

Aspirus Vascular Heart Center, Wausau

55455

Fairview Southdale Hospital/University of Minnesota Medical Center Fairview, Minneapolis

55905

Mayo Clinic, Rochester

58122

Sanford Heart Center, Fargo

73104

University of Oklahoma Health Sciences Center, Oklahoma City

75390

UT Southwestern, Dallas

77030

Texas Heart Institute, Houston

98108

Veterans Administration Puget Sound, Seattle

98195

Swedish Medical Center, Seattle

02115

Brigham & Women's Hospital, Boston

Children's Hospital Boston, Boston

Massachusetts General Hospital, Boston

02116

St. Elizabeth's Medical Center, Boston

02215

Beth Israel Deaconess Medical Center, Boston

01199

Baystate Medical Center, Springfield

08903

Robert Wood Johnson Medical School, New Brunswick

07112

Newark Beth Israel Deaconess Medical Center, Newark

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Carelon Research

OTHER