A Clinical Study Using MEDI-551 in Adult Participants With Relapsed or Refractory Advanced B-Cell Malignancies

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

April 16, 2010

Primary Completion Date

March 21, 2019

Study Completion Date

March 21, 2019

Conditions
B-cell MalignanciesCancer
Interventions
DRUG

MEDI-551

MEDI-551 will be administered intravenously (IV) once every week in 4-week cycles until complete response, disease progression, toxicity, or another reason for treatment discontinuation will be observed.

DRUG

Rituximab

Rituximab will be administered IV on Days 1, 8, 15, and 22 (28- day cycle). The treatment will be continued until the participants experiences unacceptable toxicity, disease progression, reaches complete response or withdraws consent.

Trial Locations (21)

3000

Research Site, Leuven

5530

Research Site, Yvoir

9000

Research Site, Ghent

11042

Research Site, Lake Success

17033

Research Site, Hershey

20007

Research Site, Washington D.C.

26506

Research Site, Morgantown

28033

Research Site, Madrid

28050

Research Site, Madrid

33612

Research Site, Tampa

35249

Research Site, Birmingham

41124

Research Site, Modena

44124

Research Site, Cona

53226

Research Site, Milwaukee

55905

Research Site, Rochester

60612

Research Site, Chicago

66205

Research Site, Westwood

77030

Research Site, Houston

92093

Research Site, La Jolla

08903

Research Site, New Brunswick

H3T 1E2

Research Site, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MedImmune LLC

INDUSTRY

NCT00983619 - A Clinical Study Using MEDI-551 in Adult Participants With Relapsed or Refractory Advanced B-Cell Malignancies | Biotech Hunter | Biotech Hunter