Effect of Low Dose Bortezomib on Bone Formation in Smoldering Myeloma Patients

PHASE2TerminatedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

September 30, 2014

Study Completion Date

September 30, 2014

Conditions
CancerMyelomaMultiple Myeloma
Interventions
DRUG

Bortezomib

"Bortezomib will be administered as a 3-5 second bolus IV injection at the dose of 0.7 mg/m2 on days 1, 8, 15, and 22 of each 42 day cycle.~Patients will undergo nine 42-day cycles. At the end of this (day 378), patients will be assessed for bone remodeling changes. Evaluation for toxicities will be evaluated at the beginning of each cycle."

Trial Locations (1)

84112

Huntsman Cancer Institute, Salt Lake City

Sponsors
All Listed Sponsors
collaborator

Millennium Pharmaceuticals, Inc.

INDUSTRY

lead

University of Utah

OTHER

NCT00983346 - Effect of Low Dose Bortezomib on Bone Formation in Smoldering Myeloma Patients | Biotech Hunter | Biotech Hunter