A Trial Of CVX-060, An Anti-Angiogenic COVX-Body, In Combination With Sunitinib In Patients With Advanced Renal Cell Carcinoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

September 30, 2009

Primary Completion Date

March 31, 2014

Study Completion Date

March 31, 2014

Conditions
Solid Tumor
Interventions
DRUG

CVX-060 + sunitinib

CVX-060 weekly infusions at 6.0 mg/kg + 50 mg sunitinib daily (4 out of 6 weeks)

DRUG

CVX-060 + sunitinib

CVX-060 weekly infusions at 12.0 mg/kg + 50 mg sunitinib daily (4 out of 6 weeks)

DRUG

CVX-060 + sunitinib

CVX-060 weekly infusions at 15.0 mg/kg + 50 mg sunitinib daily (4 out of 6 weeks)

DRUG

CVX-060 + sunitinib

CVX-060 weekly infusions at TBD mg/kg + 50 mg sunitinib daily (4 out of 6 weeks)

DRUG

CVX-060 + sunitinib

CVX-060 weekly infusions at TBD mg/kg + 50 mg sunitinib daily (4 out of 6 weeks)

DRUG

Sunitinib

50 mg sunitinib daily (4 out of 6 weeks)

Trial Locations (7)

38120

Boston Baskin Cancer Foundation, Memphis

38133

Boston Baskin Cancer Foundation, Bartlett

38138

Boston Baskin Cancer Foundation, Germantown

38671

Boston Baskin Cancer Foundation, Southaven

85258

Premiere Oncology of Arizona, Scottsdale

90404

Premiere Oncology, A Medical Corporation, Santa Monica

97213

Providence Portland Medical Center, Portland

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY