Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma

PHASE3CompletedINTERVENTIONAL
Enrollment

207

Participants

Timeline

Start Date

April 30, 2001

Study Completion Date

September 30, 2007

Conditions
Rectal Cancer
Interventions
RADIATION

High-Dose radiotherapy

Preoperative radiotherapy of 45 Gy/25 fractions of 1.8 Gy through three fields was delivered to the pelvis over 5 weeks, followed by a 18 Gy/10 fraction boost to the primary tumor over 2 weeks.

RADIATION

Chemo-radiotherapy

Chemotherapy (5-fluorouracil, 200 mg per square meter of body-surface area per day) was delivered over 5 weeks concurrently with the pelvic radiotherapy.

Trial Locations (12)

Unknown

Institut Sainte catherine, Avignon

Hopital Saint Andre, Bordeaux

Hotel Dieu, Clermont-Ferrand

Hopital Michallon, Grenoble

Centre Oscar Lambret, Lille

CAC Léon Bérard, Lyon

Institut Paoli Calmettes, Marseille

CRLC Val d'Aurelle, Montpellier

Hopital Saint Eloi, Montpellier

Centre Rene Gauducheau, Nantes

Centre Paul Strauss, Strasbourg

Institut Gustave Roussy, Villejuif

All Listed Sponsors
lead

Institut du Cancer de Montpellier - Val d'Aurelle

OTHER

NCT00979680 - Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma | Biotech Hunter | Biotech Hunter