Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab)

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

January 31, 2014

Study Completion Date

January 31, 2014

Conditions
Glioblastoma MultiformeAnaplastic Astrocytoma
Interventions
DRUG

Super-Selective Intraarterial Intracranial Infusion of BEVACIZUMAB

"This phase I clinical research trial will test the hypothesis that Bevacizumab can be safely used by direct intracranial superselective intraarterial infusion up to a dose of 10mg/kg to ultimately enhance survival of patients with relapsed/refractory GBM/AA.~Day 0: Intraarterial Avastin single dose (starting at 2mg/kg and up to 10mg/kg) after Mannitol to open the blood brain barrier."

Trial Locations (1)

10075

Lenox Hill Brain Tumor Center, New York

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Northwell Health

OTHER