Erlotinib Is Being Studied With Or Without An Investigational Drug, PF-02341066, In Patients With Lung Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

January 31, 2010

Primary Completion Date

December 31, 2011

Study Completion Date

January 31, 2014

Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG

Erlotinib

Erlotinib, 150 mg, QD will be administered orally on a continuous schedule (Phase 2 only)

DRUG

Erlotinib

For Phase 1 - escalating doses of erlotinib will be administered orally on a continuous schedule. The planned doses to be evaluated are 100 and 150 mg QD. The dose determined in Phase 1 will be used in Phase 2

DRUG

PF-02341066

For Phase 1 - escalating doses of PF-02341066 will be administered orally on a continuous schedule. The planned doses to be evaluated are 200 and 250 mg BID. The dose determined in Phase 1 will be used in Phase 2

Trial Locations (16)

33308

Holy Cross Hospital, Fort Lauderdale

35233

University of Alabama at Birmingham, Birmingham

35294

University of Alabama at Birmingham, Birmingham

43205

OSU East, Columbus

43210

The Ohio State University James Cancer Hospital, Columbus

43221

James Care in Kenny, Columbus

63110

Washington University, School of Medicine, St Louis

63141

Siteman Cancer Center -West County, Creve Coeur

63376

Siteman Cancer Center, City of Saint Peters

78229

Cancer Therapy & Research Center @ UTHSCSA, San Antonio

92868

University of California Irvin, Orange

98109

Seattle Cancer Care Alliance, Seattle

98195

University of Washington Medical Center, Seattle

92868-3298

University of California, Irvine Medical Center Pharmacy, Orange

University of California, Irving - Medical Center, Orange

63110-1094

Barnes-Jewish Hospital, St Louis

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY