Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors

PHASE3CompletedINTERVENTIONAL
Enrollment

399

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

March 31, 2011

Study Completion Date

March 31, 2011

Conditions
Arthritis, Rheumatoid
Interventions
DRUG

CP-690,550

Oral tablets administered at 5 mg BID daily for 6 months during the double-blind, placebo-controlled period.

DRUG

CP-690,550

Oral tablets administered at 10 mg BID daily for 6 months during the double-blind, placebo-controlled period.

DRUG

Placebo

Oral placebo tablets administered BID daily during the first 3 months of the double-blind, study period.

DRUG

CP-690,550

Oral tablets administered at 5 mg BID daily during the second 3 months of the double-blind, study period.

DRUG

Placebo

Oral placebo tablets administered BID daily during the first 3 months of the double-blind, placebo-controlled period.

DRUG

CP-690,550

Oral tablets administered at 10 mg BID daily during the second 3 months of the double-blind, study period.

Trial Locations (92)

4

Pfizer Investigational Site, Dublin

333

Pfizer Investigational Site, Kweishan

500

Pfizer Investigational Site, Changhua

813

Pfizer Investigational Site, Kaohsiung City

833

Pfizer Investigational Site, Niao Sung Hsiang

1090

Pfizer Investigational Site, Vienna

1100

Pfizer Investigational Site, Vienna

2217

Pfizer Investigational Site, Kogarah

3081

Pfizer Investigational Site, Heidelberg

3500

Pfizer Investigational Site, Hasselt

3600

Pfizer Investigational Site, Genk

4020

Pfizer Investigational Site, Liège

5041

Pfizer Investigational Site, Daw Park

10117

Pfizer Investigational Site, Berlin

14163

Pfizer Investigational Site, Berlin

15705

Pfizer Investigational Site, Santiago de Compostela

19090

Pfizer Investigational Site, Willow Grove

19610

Pfizer Investigational Site, Wyomissing

21502

Pfizer Investigational Site, Cumberland

22081

Pfizer Investigational Site, Hamburg

27804

Pfizer Investigational Site, Rocky Mount

28007

Pfizer Investigational Site, Madrid

30342

Pfizer Investigational Site, Atlanta

33180

Pfizer Investigational Site, Aventura

33614

Pfizer Investigational Site, Tampa

35294

Pfizer Investigational Site, Birmingham

37203

Pfizer Investigational Site, Nashville

37343

Pfizer Investigational Site, Hixson

37909

Pfizer Investigational Site, Knoxville

38801

Pfizer Investigational Site, Tupelo

39008

Pfizer Investigational Site, Santander

39232

Pfizer Investigational Site, Flowood

45000

Pfizer Investigational Site, Orléans

45032

Pfizer Investigational Site, Orléans

46017

Pfizer Investigational Site, Valencia

46227

Pfizer Investigational Site, Indianapolis

48013

Pfizer Investigational Site, Bilbao

48431

Pfizer Investigational Site, Rheine

48903

Pfizer Investigational Site, Barakaldo

50139

Pfizer Investigational Site, Florence

50937

Pfizer Investigational Site, Cologne

60590

Pfizer Investigational Site, Frankfurt am Main

62704

Pfizer Investigational Site, Springfield

70115

Pfizer Investigational Site, New Orleans

75014

Pfizer Investigational Site, Paris

75231

Pfizer Investigational Site, Dallas

75246

Pfizer Investigational Site, Dallas

76107

Pfizer Investigational Site, Fort Worth

77034

Pfizer Investigational Site, Houston

79424

Pfizer Investigational Site, Lubbock

80054

Pfizer Investigational Site, Amiens

83404

Pfizer Investigational Site, Idaho Falls

83702

Pfizer Investigational Site, Boise

90033

Pfizer Investigational Site, Los Angeles

90095

Pfizer Investigational Site, Los Angeles

91054

Pfizer Investigational Site, Erlangen

92108

Pfizer Investigational Site, San Diego

97080

Pfizer Investigational Site, Würzburg

98664

Pfizer Investigational Site, Vancouver

98684

Pfizer Investigational Site, Vancouver

98686

Pfizer Investigational Site, Vancouver

06030-5353

Pfizer Investigational Site, Farmington

06611

Pfizer Investigational Site, Trumbull

04102

Pfizer Investigational Site, Portland

01610

Pfizer Investigational Site, Worcester

03756

Pfizer Investigational Site, Lebanon

08043

Pfizer Investigational Site, Voorhees Township

18015-1153

Pfizer Investigational Site, Bethlehem

A-1100

Pfizer Investigational Site, Vienna

Unknown

Pfizer Investigational Site, Vienna

Pfizer Investigational Site, Kortrijk

Pfizer Investigational Site, Lyon

Pfizer Investigational Site, Paris

Pfizer Investigational Site, Croom

Pfizer Investigational Site, Iesi

74110-120

Pfizer Investigational Site, Goiânia

80060-240

Pfizer Investigational Site, Curitiba

90610-000

Pfizer Investigational Site, Porto Alegre

04266-010

Pfizer Investigational Site, São Paulo

R3A 1M3

Pfizer Investigational Site, Winnipeg

L8N 1Y2

Pfizer Investigational Site, Hamilton

L8N 2B6

Pfizer Investigational Site, Hamilton

K1H 1A2

Pfizer Investigational Site, Ottawa

H2L 1S6

Pfizer Investigational Site, Montreal

H9R 3J1

Pfizer Investigational Site, Pointe-Claire

06108

Pfizer Investigational Site, Halle

04103

Pfizer Investigational Site, Leipzig

00910

Pfizer Investigational Site, San Juan

602-715

Pfizer Investigational Site, Busan

705-718

Pfizer Investigational Site, Daegu

135-720

Pfizer Investigational Site, Seoul

06800

Pfizer Investigational Site, Mérida

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT00960440 - Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors | Biotech Hunter | Biotech Hunter