Donor Umbilical Cord Blood Transplant After Cyclophosphamide, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematologic Disease

PHASE2UnknownINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

August 31, 2012

Conditions
Hematopoietic/Lymphoid Cancer
Interventions
DRUG

cyclophosphamide

DRUG

cyclosporine

DRUG

fludarabine phosphate

DRUG

mycophenolate mofetil

OTHER

laboratory biomarker analysis

PROCEDURE

nonmyeloablative allogeneic hematopoietic stem cell transplantation

PROCEDURE

umbilical cord blood transplantation

RADIATION

total-body irradiation

Trial Locations (6)

BS2 8BJ

RECRUITING

Bristol Royal Hospital for Children, Bristol

LS16 6QB

RECRUITING

Cancer Research UK Clinical Centre at St. James's University Hospital, Leeds

NW1 2PQ

RECRUITING

University College of London Hospitals, London

WC1E 6DD

RECRUITING

UCL Cancer Institute, London

WC1N 3JH

RECRUITING

Great Ormond Street Hospital for Children, London

NE2 4HH

RECRUITING

University of Newcastle-Upon-Tyne Northern Institute for Cancer Research, Newcastle upon Tyne

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Cancer Research UK

OTHER