A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis

PHASE2CompletedINTERVENTIONAL
Enrollment

173

Participants

Timeline

Start Date

November 30, 2009

Primary Completion Date

May 31, 2012

Study Completion Date

August 31, 2012

Conditions
Sarcoidosis
Interventions
DRUG

Placebo

Matching Placebo will be administered subcutaneously (injected under the skin by way of a needle) every 4 weeks up to Week 24.

DRUG

Golimumab

Golimumab will be administered subcutaneously at a dose of 200 milligram (mg) at Week 0 and thereafter at a dose of 100 mg every 4 weeks up to Week 24.

DRUG

Ustekinumab

Ustekinumab will be administered subcutaneously at a dose of 180 mg at Week 0 and thereafter at a dose of 90 mg at Week 8, 16 and 24 and matching Placebo was administered subcutaneously at Week 4, 12 and 20.

Trial Locations (53)

Unknown

Birmingham

Los Angeles

Denver

New Haven

Chicago

Baltimore

Ann Arbor

Detroit

St Louis

Lebanon

New York

Chapel Hill

Charlotte

Greenville

Cincinnati

Cleveland

Columbus

Philadelphia

Pittsburgh

Charleston

Spartanburg

Memphis

Dallas

Colchester

Brussels

Leuven

Liège

Aarhus

Arhus C

Hellerup

København NV

Bobigny

Lille

Marseille

Montpellier

Paris

Bad Berka

Berlin

Essen

Freiburg im Breisgau

Hanover

München

Amsterdam-Zuidoost

Rotterdam

Sittard

Oslo

Trondheim

Bucharest

Bristol

London

Portsmouth

Sheffield

Southampton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Centocor, Inc.

INDUSTRY

NCT00955279 - A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis | Biotech Hunter | Biotech Hunter