Preventing Acute Chest Syndrome by Transfusion Feasibility Study

NACompletedINTERVENTIONAL
Enrollment

237

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

June 30, 2010

Study Completion Date

July 31, 2010

Conditions
Sickle Cell Disease
Interventions
BIOLOGICAL

Single blood transfusion

Participants will receive a single transfusion of 7-13cc/kg packed red blood cells (RBCs) while in the hospital.

BEHAVIORAL

Standard care

Participants will receive standard care for ACS while in the hospital.

Trial Locations (24)

Unknown

Children's Hospital and Research Center, Oakland

A.I. duPont Hospital for Children, Wilmington

Children's National Medical Center, Washington D.C.

Howard University Hospital, Washington D.C.

Emory University School of Medicine, Atlanta

Medical College of Georgia, Augusta

Children's Memorial Hospital, Chicago

University of Illinois Sickle Cell Center, Chicago

Kosair Children's Hospital, Louisville

Johns Hopkins, Baltimore

Boston Medical Center, Boston

Brigham & Women's Hospital, Boston

Children's Hospital Boston, Boston

University of Mississippi Medical Center, Jackson

Interfaith Medical Center, Brooklyn

New York Methodist Hospital, Brooklyn

The University of North Carolina at Chapel Hill, Chapel Hill

Duke University Medical Center, Durham

Cincinnati Children's Hospital Medical Center, Cincinnati

Nationwide Children's Hospital, Columbus

Ohio State University, Columbus

Children's Hospital of Philadelphia, Philadelphia

St. Christopher's Hospital for Children, Philadelphia

Virginia Commonwealth University Health Systems, Richmond

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Carelon Research

OTHER