A Study of NK012 in Patients With Advanced, Metastatic Triple Negative Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

December 31, 2014

Study Completion Date

February 28, 2015

Conditions
Triple Negative Breast Cancer
Interventions
DRUG

NK012

30 minute IV infusion once every 28 days. NK012 dose is 28 mg/m\^2 (or 18 mg/m\^2 depending on UGT1A1 polymorphism, with potential to dose escalate). Dose escalation cannot exceed 28 mg/m\^2. Dosing will proceed until progression or unacceptable toxicity develops, or decision by patient or investigator to stop.

Trial Locations (1)

37203

Sarah Cannon Research Institute, Nashville

Sponsors
All Listed Sponsors
lead

Nippon Kayaku Co., Ltd.

INDUSTRY