NCT00950651 - A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol HCl / Contramid® Tablets to Twice Daily Tramadol HCl (SR) for the Treatment of Osteoarthritis of the Knee | Biotech Hunter

Enrollment

431

Participants

Timeline

Start Date

March 31, 2002

Primary Completion Date

November 30, 2002

Study Completion Date

November 30, 2002

Conditions

Osteoarthritis, KneePain

Interventions

DRUG

Tramadol HCl Contramid® Once A Day

The patients orally self-administered the study medication: either 100, 200, 300 or 400 mg Tramadol HCl Contramid® Once A Day. Each patient was titrated to his or her optimum dose (up to a maximum of 400 mg) during the Titration Phase, which lasted between 4 and 12 days. The optimum dose was taken throughout the study.

DRUG

Tramadol HCl Twice a day

The patients orally self-administered the study medication: either 200, 300 or 400 mg Tramadol HCl Twice a day. Each patient was titrated to his or her optimum dose (up to a maximum of 400 mg) during the Titration Phase, which lasted between 4 and 12 days. The optimum dose was taken throughout the study.