Oral Appliance Therapy in Obstructive Sleep Apnea

NACompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

October 31, 2003

Primary Completion Date

January 31, 2009

Study Completion Date

July 31, 2009

Conditions
Obstructive Sleep Apnea
Interventions
DEVICE

Mandibular Advancement Device (MAD)

This oral appliance keeps the mandible and the tongue in a protruded position. This results in an upper respiratory tract widening and/or reduced collapsibility of the upper airway, thereby preventing the upper airway collapse during sleep.

DEVICE

nasal CPAP

The CPAP machine delivers a stream of compressed air via a hose to a nose mask, splinting the airway (keeping it open under air pressure) so that unobstructed breathing becomes possible, reducing and/or preventing apneas and hypopneas

DEVICE

placebo

as a placebo, a thin (\< 1 mm), hard acrylic-resin palatal splint with only a partial palatal coverage was used

Trial Locations (1)

1066 EA

Academic Centre for Dentistry Amsterdam (ACTA), Research Institute Move, University of Amsterdam and VU University Amsterdam, Amsterdam

All Listed Sponsors
lead

VU University of Amsterdam

OTHER

NCT00950495 - Oral Appliance Therapy in Obstructive Sleep Apnea | Biotech Hunter | Biotech Hunter