Effect of Pimecrolimus Cream on Cathelicidin Levels in Subjects With Eczema

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

February 28, 2011

Study Completion Date

May 31, 2011

Conditions
Atopic Dermatitis
Interventions
DRUG

Pimecrolimus

"20 AD patients will be given pimecrolimus 1% to apply twice daily for up to three weeks on each lesional site predetermined at baseline. Lesional target site and non-lesional site will be determined at Visit 1.~Two 2 mm biopsies will be obtained from a target AD lesion and non-lesional sites at Visit 2, and Visit 3 (four biopsies each visit)."

OTHER

Vehicle cream

"20 AD patients will be treated with vehicle cream twice daily for up to 3 weeks on each lesional site predetermined at baseline. Lesional target site and non-lesional site will be determined at Visit 1.~Two 2 mm biopsies will be obtained from a target AD lesion and non-lesional sites at Visit 2, and Visit 3 (four biopsies each visit)."

Trial Locations (1)

92037

University of California, San Diego - Dept of Dermatology, La Jolla

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

University of California, San Diego

OTHER

NCT00946478 - Effect of Pimecrolimus Cream on Cathelicidin Levels in Subjects With Eczema | Biotech Hunter | Biotech Hunter