Combination Chemotherapy With CS-1008 to Treat Ovarian Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

October 6, 2009

Primary Completion Date

August 23, 2011

Study Completion Date

August 23, 2011

Conditions
Ovarian Cancer Stage IIICOvarian Cancer Stage IV
Interventions
DRUG

CS-1008

CS-1008 intravenous (IV) infusion 10 mg/kg on Day 1 of Cycle 1 and 8 mg/kg once every 3 weeks (1 cycle) for Cycle 2-6

DRUG

Paclitaxel

Paclitaxel 175 mg/m\^2 IV infusion once every 3 weeks (1 cycle) for 6 cycles

DRUG

Carboplatin

Carboplatin (target area under the concentration versus time curve of 6.0 mg/mL/min using the Calvert Formula) IV infusion once every 3 weeks (1 cycle) for 6 cycles

Trial Locations (3)

35233

Univ. Alabama, Birmingham

63110

Barnes Jewish Hospital, St Louis

73104

University of Oklahoma, Oklahoma City

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Daiichi Sankyo

INDUSTRY