Valsartan/Amlodipine As Compared to Losartan Treatment in Stage 2 Systolic Hypertension

PHASE4CompletedINTERVENTIONAL
Enrollment

488

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

January 31, 2010

Study Completion Date

January 31, 2010

Conditions
Stage 2 Systolic Hypertension
Interventions
DRUG

valsartan, amlodipine, HCTZ

combination Valsartan/amlodipine160/5 mg tablet for 3 weeks; Valsartan/amlodipine 160/5mg tablet +HCTZ 25 mg capsule for 3 weeks; valsartan/amlodipine 320/10 mg tablet + HCTZ 25mg capsule for remainder (6 weeks) of the study

DRUG

Losartan, HCTZ followed by valsartan, amlodipine, HCTZ

losartan 100mg capsule for 3 weeks; losartan 100mg capsule +HCTZ 25 mg capsule for 3 weeks; Valsartan/amlodipine 160/5mg tablet +HCTZ 25 mg capsule for 3 weeks; valsartan/amlodipine 320/10 mg tablet + HCTZ 25mg capsule for remainder (3 weeks) of the study

Trial Locations (1)

Unknown

sites in USA, East Hanover

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novartis

INDUSTRY