63
Participants
Start Date
September 30, 2002
Primary Completion Date
April 30, 2008
Study Completion Date
May 31, 2008
lateral internal sphincterotomy (LIS)
closed lateral internal sphincterotomy was done under local anesthesia at 3 o'clock in lithotomy position reaching up to the dentate line.
Glycerin trinitrate (GTN)
All were instructed to apply the GTN ointment 0.2 % twice a day to the edge and just inside the anal canal for 8 week course.
botulinum toxin injection (BTX A)
All were injected with botulinum toxin injection (BTX- A) in the left lateral position; anesthesia was not required. A volume of 0.5 ml of dissolved toxin, i.e., 100 u Dysport, is injected in each patient. The injection is given with an insulin syringe fitted with a needle size of 21 gauze and 3.75 lengths. Injection into the IAS, with the patients awake in the left -lateral position in the outpatient clinic in the 3 and 9 o'clock position.
Ayman Elnakeeb, Al Mansurah
Mansoura University
OTHER