Idiopathic Hypertensive Anal Canal: a Place of Internal Sphincterotomy

NACompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

September 30, 2002

Primary Completion Date

April 30, 2008

Study Completion Date

May 31, 2008

Conditions
Hypertensive Anal Canal
Interventions
PROCEDURE

lateral internal sphincterotomy (LIS)

closed lateral internal sphincterotomy was done under local anesthesia at 3 o'clock in lithotomy position reaching up to the dentate line.

DRUG

Glycerin trinitrate (GTN)

All were instructed to apply the GTN ointment 0.2 % twice a day to the edge and just inside the anal canal for 8 week course.

DRUG

botulinum toxin injection (BTX A)

All were injected with botulinum toxin injection (BTX- A) in the left lateral position; anesthesia was not required. A volume of 0.5 ml of dissolved toxin, i.e., 100 u Dysport, is injected in each patient. The injection is given with an insulin syringe fitted with a needle size of 21 gauze and 3.75 lengths. Injection into the IAS, with the patients awake in the left -lateral position in the outpatient clinic in the 3 and 9 o'clock position.

Trial Locations (1)

335111

Ayman Elnakeeb, Al Mansurah

All Listed Sponsors
lead

Mansoura University

OTHER

NCT00927849 - Idiopathic Hypertensive Anal Canal: a Place of Internal Sphincterotomy | Biotech Hunter | Biotech Hunter